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| The following is a list of terms and acronyms used in Haematology and Oncology: |
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-------------------------------------------------------------Diseases------------------------------------------------
AA - aplastic anemia ALL - acute lymphocytic leukemia (+3 subtypes according to morphology.L1-L3 and subtypes according to phenotype: T, pre-B, pre-pre-B, B) AML acute myelogeneous leukemia (+8 subtypes MO-M6) AMML - acute myelogeneous leukemia ANLL - acute non-lymphocytic leukemia (included in AML above) APL - acute prolymphocytic leukemia APML - acute promyelocytic leukemia BCP-ALL - B-cell precursor acute lymphoblastic leukemia CLL - chronic lymphocytic leukemia CML - chronic myeloid leukemia (each has subtypes) CNSL - central nervous system lymphoma HCL - hairy cell leukemia HD - Hodgkins lymphoma (4 subtypes) MCL - mantle cell lymphoma MDS - myelodysplastic syndrome (4 subtypes) MF - mycosis fungoides (cutaneous T-cell lymphoma) MM - multiple myeloma MPD - myeloproliferative disorders NHL - non-Hodgkins lymphoma (many subtypes) PV - polycythemia vera WM - Waldenstrom's Macroglobulinemia ---------------------------------------------------Treatment Options--------------------------------------------- ABMT - autologous bmt- your own marrow BMT - allogeneic bmt- someone else's marrow SBMT - syngeneic bmt- identical twin's marrow MUD - a transplant using a matched unrelated donor PBPC - peripheral blood progenitor cell transplant (which is becoming the new standard term ) PBSCT - peripheral blood stem cell transplant PBSCR - peripheral blood stem cell rescue PSCT or PSCR - The same as above without the word "blood." -------------------------------------------------Chemotherapies-------------------------------------------------- ACOB - doxorubicin, cyclophosphamide, vincristine, bleomycin ABVD - doxorubicin, vinblastine, bleomycin,DTIC ARA-C - cytarabine ATRA - all-trans retinoic acid, or Vesanoid BACOP - bleomycin, doxorubicin, cyclophosphamide, vincristine, prednisone BEAM - busulfan, etoposid, ara-c, melphalan BLEO - bleomycin 2CdA - 2-chlorodeoxyadenosine (Generic name = cladribine) C-MOPP - cyclophosphamide, oncovin, procarbazine, prednisone CCNU - (1-2-chloroethyl)-3-cyclohexyl-1-nitrosourea) CHOD - cyclophosphamide, doxorubicin, vincristine, dexamethasone CHOP - cyclophosphamide, adriamycin, vincristine, prednisone CHOP-BLEO - cyclophosphamide, doxorubicin, vincristine, prednisone and bleomycin CMF - cyclophosphamide, methotrexate, fluorouacil COP - cyclophosphamide, vincristine, prednisone COPP - CCNU, - vincristine,procarbazine, prednisone CyA - cyclosporin A DCF - 2-deoxycoformycin (pentostatin) DTIC - dacarbazine, 5-(3,3-dimethyl-1-triazino)imidazole-4- carboxamide EPOCH - etopside, prednisone, vincristine, cyclophosphamide (cytoxan), adriamycin FAC - fluorouacil, adriamycin, cyclophosphamide Flu - fludarabine (Fludara) IFN - Interferon (comes in alpha2a, alpha 2b, human leukocyte, and beta-- Another one "concensus" is still in trials) IL - Interleuken mBACOD methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, dexamethasone MOPP - nitrogen mustard, vincristine, procarbazine, prednisone MTX - or M methotrexate proMACE - prednisone, methotrexate with leukovorin rescue, doxorubicin, cyclophosphamide, etoposide (VP-16) -----------------------------------------------Blood Stimulating Factors------------------------------------- EPOIETIN - erythropoietin (Epogen)-- is used to stimulate red cell growth. G-CSF - granulocyte colony stimulating factor (Neupogen)- stimulates growth of white cells . GM-CSF - granulocyte macrophage - colony stimulating factor (sargramostim) NEUMEGA - platelet stimulating factor TPOIETIN - thrombopoietin - (platelet stimluating factor) --still in clinical trials. ---------------------------------------------------General Terminology--------------------------------------- BMB - bone marrow biopsy BMT - bone marrow transplant (see specifics listed above) B2M - beta 2 microglobulin test. Beta-2-microglobulin is a protein found on all the surface of all cells and small amounts are shed into the serum. People diagnosed with blood diseases and who have levels of beta-2-microglobulin below 3.0 seem to have a longer survival rate. CCDRT - cell culture drug resistance testing EPOIETIN - erythropoietin (Epogen)-- is used to stimulate red cell growth. FISH - Fluorescence In Situ Hybridization.It is a test used to detect chromosone abnormalities in cells and has been used to test lymphocytes in CLL. The results help to predict the prognosis for a particular patient. G-CSF - granulocyte - colony stimulating factor (Neupogen)- stimulates growth of white cells GM-CSF - granulocyte macrophage - colony stimulating factor (sargramostim) GVHD - graft vs host disease GVL graft vs leukemia or graft vs lymphoma HDC - high dose chemotherapy--often used to condition one before a BMT or PBSCT Ig - Immunoglobulin (IgA, IgD, IgE, IgG, IgM) IV - intravenous--into a vein Mab or MoAb - monoclonal antibodies (i.e. Campath-1H, Rituxan, Bexxar) MUD - matched unrelated donor of bone marrow Neumega - a platelet growth factor NR - nodular remission (nodules of cancer cells remain in the marrow, but there are less than 10% cancer cells throughout) OR - overall remission PBSCR - peripheral blood stem cell rescue --same as PBSCT PBSCT - peripheral blood stem cell transplant PR - partial remission TPOIETIN - thrombopoietin - (platelet stimluating factor) ----------------------------------------------------General Acronyms----------------------------------------- Bx - Biopsy B/P - Blood Pressure CR - complete remission CRN - complete remission with nodular pattern in marrow CS - Clinical Stage CBC - Complete Blood Count Dx - Diagnosis HCT - Hematocrit The percentage of red blood cells in the blood. A low hematocrit measurement indicates anemia. Hem/Onc - hematologist/oncologist HGB - hemoglobin HLA - Human leukocyte antigen test A special blood test used to match a blood or bone marrow donor to a recipient for transfusion or transplant. IV - intravenous, placed directly into a vein OR - overall remission PR - partial remission RBC - red blood count RX - prescribed medication WBC - white blood count WBC/HPF - white blood cells counted per high powered field WD - well differentiated WW - watch and wait (also called, watch and worry) XRT - external radiation therapy Disclaimer: The information provided here is as accurate and up-to-date as we have been able to make it. We are constantly striving to ensure its accuracy and we welcomeyour suggestions and corrections. The information is provided purely for educational purposes and should be discussed with your own physician. Reproduced from an article in BMT-Talk, January 1999 
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